Giuseppe R. Diaferia

BIO

I obtained my M.Sc. in Medical Biotechnologies and the PhD in Molecular Medicine at the University of Milan. I developed a strong theoretical and technical background in developmental biology starting from my PhD training at the National Council of Researches in Milan and at the University of California San Diego, UCSD (USA) where I continued, after my PhD, to work on pancreatic development in health and disease. Back in Italy, I focused my research on pancreatic tumor grading by reverse epigenomic approaches at Humanitas University and at the European Institute of Oncology in Milan.

RESEARCH

PDAC is a highly heterogenous tumor with different type on cancer cells that coexist in the same tumor. Each type has different growth properties and chemoresistance potential which lead to the failure of the actual therapeutic strategies. My efforts are concentrated on the study of the mechanism governing pancreatic tumor heterogeneity and in the spatial relationship between tumor cells with different gene expression profiles and non-tumor components. Using novel approaches that maintain tissue integrity we are aiming to perform gene expression analysis of defined tumor anatomical areas to identify new molecular target for precision medicine.

https://www.research.ieo.it/research-and-technology/clinical-technoshots/clinical-technoshot-in-situ-tumor-cell-transcriptomes/

HOBBIES/EXTRAS

Juggling your personal life, your social life, and your work is hard, so I tried to improve my juggling skills with balls, clubs and balloons and, to get a new perspective on life… why not doing it walking on stilts? It might not improve your time management, but the kids will love it.