Hereditary genetic mutations
Disorders studied for pancreatic cancer connections include: BRCA mutation, cystic fibrosis, familial adenomatous polyposis, familial atypical multiple melanoma, Lynch syndrome, hereditary pancreatitis, PALB2 mutation, and Peutz-Jeghers syndrome.
Family history of pancreatic cancer
If a person has two or more first-degree relatives (mother, father, brother, or child) who have had pancreatic cancer or a first-degree relative who developed pancreatic cancer before age 50, you may be at a higher risk. to develop pancreatic cancer.
Family history of other cancers
The risk of pancreatic cancer increases if there is a family history of ovarian, breast or colon cancer, hereditary pancreatitis or familial melanoma.
Diabetes
Pancreatic cancer is more likely to occur in people who have long-standing (more than 5 years) diabetes. This can also be a symptom.
Pancreatitis
Chronic pancreatitis indicates an increased risk of developing pancreatic cancer. It is even higher in individuals with hereditary pancreatitis.
Smoking
People who smoke cigarettes are twice as likely to develop pancreatic cancer than people who have never smoked.
Obesity
Obese people have a 20% higher risk of developing pancreatic cancer than people of normal weight.
Ethnicity
African Americans and Ashkenazi Jews have a higher incidence of pancreatic cancer than individuals of Asian, Hispanic, or Caucasian descent.
Age
The chances of developing pancreatic cancer increase with age. Most people diagnosed with pancreatic cancer are over the age of 60.
Diet
Although more research is needed, a diet rich in red and processed meats can increase the risk of developing pancreatic cancer. A diet rich in fruits and vegetables can reduce the risk.