BIO
Dr Vincenzo Corbo is assistant professor at the Department of Diagnostics and Public Health, University of Verona, Italy. He received his PhD from the University of Verona in 2009. In Verona, he contributed to set up next generations sequencing platforms in the lab of Professor Aldo Scarpa, where he participated to international efforts (ICGC, International Cancer Genome Consortium) to describe somatic alterations of pancreas cancers. He completed his training as Post-Doc in the laboratory of Prof David Tuveson at Cold Spring Harbor Laboratory, NY (USA), where he participated to the development of a novel three-dimensional culture system to study pancreatic cancer. During his post-doctoral training, he also developed a therapeutic platform availing of organoids and participated to the definition of a novel-coculture system.
RESEARCH
Corbo’ lab uses different experimental models of pancreatic cancer to investigate the determinants of malignant progression with the ultimate goal of favoring the identification of new diagnostic and therapeutic approaches. The lab functional studies rely on the use of mouse and human organoid cultures, which enable the growth of both neoplastic and non-neoplastic cells from pancreatic tissues. Current projects focus on the identification and characterization of signaling pathways involved in tumor-stoma crosstalk and in the evolution of the disease centered around mechanisms of transdifferentiation and cell plasticity. The lab is part of international consortia, including the EU-funded project PRECODE and the NCI-sponsored Human Cancer Model Initiative.
HOBBIES / EXTRAS
Travel, movies, books.